Effects of prehospital adrenaline administration on out-of-hospital cardiac arrest outcomes: a systematic review and meta-analysis

Table 2 Pooling effects of prehospital adrenaline on prehospital ROSC

Author, year [reference]	Sample size	Adrenaline group		Non-adrenaline group		RR (95% CI)
Author, year [reference]	Sample size	ROSC^a	n	ROSC^a	n	RR (95% CI)
Yanagawa, 2010 [15]	713	14	58	54	655	2.93 (1.74, 4.94)
Hagihara, 2012 [12]	417,188	2,786	15,030	23.042	402,158	3.24 (3.12, 3.35)
Hayashi, 2012 [13]	3,161	297	1,013	287	2,148	2.19 (1.9, 2.53)
Nordseth, 2012 [14]	174	39	101	14	73	2.01 (1.18, 3.43)
Goto, 2013 [36]	209,577	4,563	23,676	8,674	185,901	4.13 (4.0, 4.27)
Neset, 2013 [35]	223	29	119	12	104	2.11 (1.14, 3.92)
Pooled	421,459	3,165	16,321	23,409	405,138	2.89 (2.36, 3.54)

^aPrehospital ROSC. CI, confidence interval; n, number; ROSC, return of spontaneous circulation; RR, risk ratio.

ISSN: 1364-8535