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Table 2 Treatment of invasive aspergillosis in non-neutropenic ICU patients[48]

From: How to manage aspergillosis in non-neutropenic intensive care unit patients

Setting

First choice

Alternatives

Primary therapy

Voriconazole (6 mg/kg every 12 hours intravenously on day 1, then 4 mg/kg every 12 hours intravenously)

Liposomial amphotericin B (3–5 mg/kg/day intravenously) or Echinocandins (usual dosage)

Salvage therapy

Combination of voriconazole plus amphotericin B/echinocandins