Insulin treatment guided by subcutaneous continuous glucose monitoring compared to frequent point-of-care measurement in critically ill patients: a randomized controlled trial

Table 4 Cost analysis

	Costs per unit	Factor control group	Costs in control group	Factor intervention group	Costs in intervention group	Difference in costs (95% CI)¹
Nursing time	€38/hr	36 min	€22.98	17 min	€10.87	€-12.11(−16, −9)
CGM receiver	€1009.59	-	-	€1.38 per day²	€1.38	€1.38
CGM sensor	€61.00	-	-	€24.40 per day³	€24.40	€24.40
CGM calibration⁴	€1.19	-	-	3.3	€3.95	€3.95 (3,5)
Accu-Chek Inform II device	€892.37	€1.22 per day²	€1.22	-	-	€-1.22
Material POC measurement⁵	€0.70	12.2	€8.51	0.06	€0.04	€-8.47 (−10, −7)
Laboratory⁶	€1.66	12.2	€20.18	0.06	€0.10	€-20.08 (−23, −18)
Total costs			€52.89		€40.74	€-12.42 (−22, −5)

Factors and costs are expressed as means per patient per day (24 hours). ¹95% confidence interval based on 1,000 stratified bootstrap samples; ²assuming a lifetime of two years; ³assuming a manufacturers’ sensor lifetime of two and a half days; ⁴calibration strip CGM; ⁵includes syringes, nonsterile gloves, gauzes, alcohol, cap (used for blood sampling) and testing strip POC; ⁶costs for a single point-of-care glucose measurement. CGM: continuous glucose monitoring, POC: point-of-care.

ISSN: 1364-8535