- Paper Report
- Open Access
Percutaneous needle aspiration for diagnosis of pulmonary infection
- Adrian Mellor1
© Current Science Ltd 2000
- Published: 30 June 2000
- CT guided percutaneous needle aspiration
- pulmonary infection
Pulmonary infections are a common cause of morbidity in immunocompromised patients. The use of empirical treatment can be potentially hazardous and so a bacterial diagnosis is of great benefit. Techniques such as bronchoalveolar lavage (BAL) and nasopharyngeal aspiration may produce contaminated samples and are difficult in nonintubated patients. Open lung biopsy is sometimes employed for diagnosis but has a high complication rate (8-20%). CT guided percutaneous needle biopsy has not been previously studied in advancing the microbiological diagnosis in such patients.
Retrospective review of 21 patients (24 procedures)
Target lesion located with local anaesthesia, a 20G needle under CT guidance
Aspirated material visually inspected and aspirate repeated if sample appeared inadequate
Cytologic evaluation and culture for aerobic and anaerobic bacteria, Mycobacterium sp and fungi were performed
Presence and duration of empiric antibiotic therapy prior to investigation was recorded
Patients were assigned to positive and negative yield groups
Identification of one or more species of pathogens was made in 19 of 24 samples (79.2%)Five aspirates yielded mixed inflammatory cells and had no bacterial or fungal growth.Bacteria isolated included Staphyloccus aureus (4), Mycobacterium tuberculosis (3), Pseudomonas aeruginosa (2), Streptococcus pneumoniae (1) and Klebsiella pneumoniae (1).Fungi isolated were Aspergillus fumigatus (7), Cryptococcus neoformans (1) and Candida albicans(1).Two organisms were found in one patient.A small asymptommatic pneumothorax occurred on one occasion but did not require treatment.