- Paper Report
- Open Access
Predisposition to decreased SjvO2on cardiac bypass
- Adrian Mellor1
© Current Science Ltd 2000
- Published: 13 June 2000
- Cerebral ischaemia
- extracorporeal circulation
- metabolic disorder
- neurologic complication.
Central nervous system (CNS) complications are a major cause of morbidity and mortality following cardiac surgery. DM and previous cerebrovascular disease are both common in patients presenting for cardiac surgery and these patients are thought to have a higher risk of neurological damage following surgery. This controlled study examines whether these two factors lead to alterations in SjvO2, when factors affecting cerebral perfusion are maintained within fixed limits.
Prospective study with age matched controls in patients undergoing elective coronary artery surgery with CPB
Nineteen controls, nine with previous stroke and ten with DM
SjvO2 monitored continuously from induction to end of procedure
Normothermic CPB used
PaCO2, haematocrit and mean arterial pressure maintained
Intraoperative epiaortic scanning to exclude thrombus
There were no cases of postoperative neurological deterioration. SvjO2 decreased significantly in the group with previous DM or cerebrovascular disease at 20 min and 40 min after the start of CPB. This reduction was also significant when compared to the pre-CPB values in these patients. There was no difference between the DM and stroke groups.