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  • Paper Report
  • Open Access

Unstable angina pectoris

  • Richard Venn
Critical Care20002:4432

Published: 22 February 2000




This excellent review looks at the pathogenesis, medical management and revascularisation procedures involved in this coronary syndrome. The trials involving aspirin, ticlopidine, clopidogrel, platelet glycoprotein IIb/IIIa receptor antagonists and antithrombin therapies in unstable angina are highlighted, and conventional medical therapies discussed (beta-blockers, nitrates and calcium-channel blockers). The changing attitudes regarding revascularisation procedures, with the advent of coronary stenting and glycoprotein IIb/IIIa receptor inhibition, are explored. In addition, investigations are summarised which stratify the risk of further coronary events and influence decisions on whether medical management can be safely continued, or whether angiography and myocardial revascularisation procedures are required. Finally a flow diagram of treatment strategies is presented which stratifies patients into low, intermediate and high risk groups.


  1. Yeghiazarians Y, Braustein JB, Askari A, Stone PH: Unstable angina pectoris. New Engl J Med . 1999, 342: 101-114.View ArticleGoogle Scholar


© Current Science Ltd 2000