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Table 1 Clinical characteristics of the studying populations

From: High levels of circulating leukocyte microparticles are associated with better outcome in acute respiratory distress syndrome

Variables Spontaneous breathing controls Ventilated controls ARDS patients P-value
Number of subjects 12 10 52  
Age (years, mean ± SD) 59 ± 13 58 ± 14 58 ± 17 0.98
Male sex (n, %) 8 (61) 6 (60) 39 (75) 0.78
SAPS II (mean ± SD) - 48 ± 13 47 ± 14 0.91
SOFA score (median (IQR)) - 7 (7 to 11) 10 (7 to 12) 0.11
Admission category (n, %) -    0.28
Medical   10 (100) 42 (80)  
Surgical   0 (0) 10 (20)  
Direct lung injury (n, %) - - 47 (90) -
Cause of ARDS (n, %)     -
Pneumonia - - 38 (73)  
Aspiration - - 6 (12)  
Lung contusion - - 3 (6)  
Extra pulmonary sepsis - - 5 (9)  
Reason for ICU hospitalization (n, %) -   -  
Coma   4 (40)   -
Self-poisoning   3 (30)   
CNS infections   2 (20)   
Epilepsy   1 (10)   
LISS at inclusion (median (IQR)) - 0.75 (0.44 to 1) 3 (2.5 to 3.25) <0.001
Septic shock at inclusion (n, %) - 6 (60) 43 (83) 0.44
Days under mechanical ventilation before inclusion (median (IQR)) - 2 (0 to 7) 1 (0 to 1) 0.14
  1. ARDS, acute respiratory distress syndrome; CNS, central nervous system; IQR, interquartile range; LISS, lung injury severity score; SAPS II, Simplified acute physiology score II; SD, standard deviation; SOFA score, Sequential Organ Failure Assessment score.
  2. Septic shock was defined as a systolic blood pressure of ≤ 90 mm Hg, despite adequate volume expansion requiring the use of vasopressor agents; P-values compare ventilated controls and ARDS patients.