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Table 1 Clinical characteristics of the studying populations

From: High levels of circulating leukocyte microparticles are associated with better outcome in acute respiratory distress syndrome

Variables

Spontaneous breathing controls

Ventilated controls

ARDS patients

P-value

Number of subjects

12

10

52

 

Age (years, mean ± SD)

59 ± 13

58 ± 14

58 ± 17

0.98

Male sex (n, %)

8 (61)

6 (60)

39 (75)

0.78

SAPS II (mean ± SD)

-

48 ± 13

47 ± 14

0.91

SOFA score (median (IQR))

-

7 (7 to 11)

10 (7 to 12)

0.11

Admission category (n, %)

-

  

0.28

Medical

 

10 (100)

42 (80)

 

Surgical

 

0 (0)

10 (20)

 

Direct lung injury (n, %)

-

-

47 (90)

-

Cause of ARDS (n, %)

   

-

Pneumonia

-

-

38 (73)

 

Aspiration

-

-

6 (12)

 

Lung contusion

-

-

3 (6)

 

Extra pulmonary sepsis

-

-

5 (9)

 

Reason for ICU hospitalization (n, %)

-

 

-

 

Coma

 

4 (40)

 

-

Self-poisoning

 

3 (30)

  

CNS infections

 

2 (20)

  

Epilepsy

 

1 (10)

  

LISS at inclusion (median (IQR))

-

0.75 (0.44 to 1)

3 (2.5 to 3.25)

<0.001

Septic shock at inclusion (n, %)

-

6 (60)

43 (83)

0.44

Days under mechanical ventilation before inclusion (median (IQR))

-

2 (0 to 7)

1 (0 to 1)

0.14

  1. ARDS, acute respiratory distress syndrome; CNS, central nervous system; IQR, interquartile range; LISS, lung injury severity score; SAPS II, Simplified acute physiology score II; SD, standard deviation; SOFA score, Sequential Organ Failure Assessment score.
  2. Septic shock was defined as a systolic blood pressure of ≤ 90 mm Hg, despite adequate volume expansion requiring the use of vasopressor agents; P-values compare ventilated controls and ARDS patients.
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