Table 1 Demographic and clinical characteristics of the 92 septic patients enrolled in the study.
From: Inhibition of caspase-1 activation in gram-negative sepsis and experimental endotoxemia
Gender (male/female) | 48/44 |
Age (years, mean ± SD) | 65.59 ± 19.88 |
APACHE II score (mean ± SD) | 14.36 ± 7.48 |
Sepsis stage (number, %) | |
Uncomplicated sepsis | 49 (53.3) |
Severe sepsis | 26 (28.3) |
Septic shock | 17 (18.5) |
Underlying infection (number, %) | |
Acute pyelonephritis | 38 (41.3) |
Primary bacteremia | 27 (29.3) |
Acute intrabdominal infections | 27 (29.3) |
Co-morbidities (number, %) | |
Diabetes melliitus type 2 | 15 (16.3) |
Chronic obstructive pulmonary disease | 6 (6.5) |
Chronic renal failure | 9 (9.8) |
Chronic heart failure | 7 (7.6) |
Implicated pathogen* (number, %) | |
Escherichia coli | 21 (22.8) |
Klebsiella pneumoniae | 11 (11.9) |
Other Gram-negatives | 11 (11.9) |
Death (number, %) | 22 (23.9) |