Figure 6
From: Inhibition of caspase-1 activation in gram-negative sepsis and experimental endotoxemia
Release of pro-inflammatory cytokines from PBMCs of 10 healthy controls and of 25 septic patients. Patients with sepsis (n = 12) with severe sepsis (n = 10) and with septic shock (n = 3) are encountered together. Cells were stimulated with single 0.1 ng/ml of lipopolysaccharide of Escherichia coli O55:H5 (LPS) or its interaction with 10 μg/ml of monosodium urate (MSU). Asterisks denote statistically significant differences compared with single LPS.