Figure 5
From: Inhibition of caspase-1 activation in gram-negative sepsis and experimental endotoxemia
Release of pro-inflammatory cytokines from PBMCs of 13 healthy controls and of 40 septic patients. Patients with sepsis (n = 20), with severe sepsis (n = 14) and with septic shock (n = 6) are encountered together. Cells were stimulated with 100 μg/ml of monosodium urate (MSU) in the presence of 10 ng/ml of lipopolysaccharide of Escherichia coli O55:H5 (LPS). P signifies statistical differences between patients.