Figure 4
From: Inhibition of caspase-1 activation in gram-negative sepsis and experimental endotoxemia
Release of pro-inflammatory cytokines from PBMCs of 13 healthy controls and of 40 septic patients. Patients with sepsis (n = 20,) with severe sepsis (n = 14) and septic shock (n = 6) are encountered together. Cells were stimulated with 10 ng/ml of lipopolysaccharide of Escherichia coli O55:H5 in the absence or presence of caspase-1 inhibitor. Asterisks denote statistically significant differences of respective comparisons in the absence of inhibitor.