Table 1 Randomized controlled trials of selective decontamination of the digestive tract (SDD)a,b
Author | n | VAP incidence (versus control) - % | P-value | Mortality (versus control) - % | P-value |
|---|---|---|---|---|---|
Kerver [13] | 96 | 12 vs. 85% | < 0.001 | 29 vs. 32% | NS |
Ledingham [14] | 324 | 2 vs. 11% | 0.006 | 24 vs. 24% | NS |
Ulrich [15] | 100 | 15 vs. 50% | < 0.001 | 31 vs. 54% | < 0.02 |
Aerdts [16] | 88 | 0 vs. 26% | 0.0001 | 12 vs. 15% | NS |
Blair [17] | 331 | 7 vs. 26% | 0.002 | 15 vs. 19% | NS |
Hartenauer [18] | 200 | 10 vs. 45% | < 0.01 | 31 vs. 36% | NS |
Gastinne [19] | 445 | 12 vs. 15% | NS | 34 vs. 30% | NS |
Cockerill [20] | 150 | 4 vs. 5% | NS | 11 vs. 19% | NS |
Hammond [21] | 322 | 7 vs. 6% | NS | 12 vs. 12% | NS |
Jacobs [22] | 91 | 0 vs. 9% | NS | 39 vs. 54% | NS |
Rocha [23] | 101 | 15 vs. 46% | < 0.001 | 21 vs. 44% | < 0.05 |
Winter [24] | 183 | 3 vs. 18% | < 0.05 | 36 vs. 43% | NS |
Ferrer [25] | 80 | 18 vs. 24% | NS | 31 vs. 27% | NS |
Palomar [26] | 83 | 17 vs. 50% | 0.005 | 24 vs. 31% | NS |
Verwaest [27] | 660 | 9 vs. 18% | 0.026 | 18 vs. 17% | NS |
Sánchez-GarcÃa [28] | 271 | 11 vs. 29% | < 0.001 | 39 vs. 47% | NS |
Krueger [29] | 546 | 2 vs. 11% | 0.007 | 20 vs. 29% | NS |