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Table 1 Description of RIFLE [1] and AKIN [2] definition criteria for AKI used in analysis

From: Clinical accuracy of RIFLE and Acute Kidney Injury Network (AKIN) criteria for acute kidney injury in patients undergoing cardiac surgery

Definition System

AKI

RIFLE

Class R (risk)

Class I (injury)

Class F (failure)

Seven-day interval

sCr ≥1.5-fold increase or eGFR >25% decrease compared to baseline

sCr ≥2-fold increase or eGFR >50% decrease compared to baseline

sCr ≥3-fold increase or eGFR >75% decrease compared to baseline, or sCr increase to ≥4 mg/dL in setting of an increase of ≥0.5 mg/dL

AKIN

Stage 1

Stage 2

Stage 3

48-hour moving window

sCr ≥1.5-fold increase or ≥ 0.3 mg/dL

sCr ≥2-fold increase

sCr ≥3-fold increase compared to baseline, or sCr increase to ≥4 mg/dL in setting of an increase of ≥0.5 mg/dL, or RRT

  1. AKI, acute kidney injury; eGFR, estimated glomerular filtration rate; RRT, renal replacement therapy; sCr, serum creatinine.