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Table 9 Correlation coefficients (r) between thrombomodulin (TM) and multiple organ failure (MOF) score, parameters related to coagulation and fibrinolysis*

From: Close relationship of tissue plasminogen activator-plasminogen activator inhibitor-1 complex with multiple organ dysfunction syndrome investigated by means of the artificial pancreas

 

r

P

n

MOF score

0.92

< 0.002

17

DIC score

0.80

< 0.002

17

tPA-PAI-1 complex

0.85

< 0.002

17

TAT

0.85

< 0.002

17

PLT

-0.58

< 0.01

17

FDP

0.50

< 0.04

17

D-Dimer

0.48

< 0.05

17

PAI-1 antigen

0.40

< 0.11

17

Protein C activity

-0.38

< 0.13

17

Protein S activity

-0.36

< 0.16

17

PIC

0.33

< 0.20

17

Fibrinogen

-0.31

< 0.23

17

Plasminogen

-0.31

< 0.23

17

Protein C antigen

-0.3

< 0.25

17

AT-III

0.27

< 0.41

12

PT ratio

-0.25

< 0.38

15

Protein S antigen

-0.15

< 0.57

17

PAI-1 activity

-0.04

< 0.90

12

  1. * Mean of TM, 7.3 ± 4.2 FU/ml (n = 17); normal range, ≤ 4.5. AT-III, antithrombin-III; DIC, disseminated intravascular coagulation; FDP, fibrin and fibrinogen degradation products; PAI-1, plasminogen activator inhibitor-1; PIC, α2 plasmin inhibitor-plasmin complex; PLT, platelet count; PT, prothrombin time; TAT, thrombin-antithrombin complex; tPA, tissue plasminogen activator.
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Critical Care

ISSN: 1364-8535