- Poster presentation
- Open Access
- Published:
Levels of serum B12, folic acid and homocysteine in thromboembolic diseases on admission to the Emergency Department
Critical Care volume 15, Article number: P14 (2011)
Introduction
The aim of this study was to compare with control and each other the levels of serum B12, folic acid and homocysteine at admission in the cases with thromboembolic diseases.
Methods
This study included 100 subjects with acute myocardial infarctus (AMI), acute pulmonary embolism, deep vein thrombosis, ischemic cerebrovascular disease (ICD), acute mesentery embolism, and peripheric artery embolism (PAE), and 110 healthy voluntary subjects were included in the control group. Vitamin B12, folic acid and homocysteine levels were examined in the blood samples obtained at admission, The data were loaded onto SPSS 16 for Windows program. P ≤ 0.05 was considered significant.
Results
Mean serum homocysteine and plasma vitamin B12 levels were significantly higher in the patient group than the control group (P = 0.002 and 0.000 respectively). There was no significant difference in the levels of folic acid between the patient and control groups. Mean serum B12 values of the AMI and ICD groups in the patient group were significantly lower than those of the control group (P < 0.05). Serum folic acid values of the PAE and AMI groups were considerably lower than the control group (P < 0.05). Plasma homocysteine levels were significantly higher in all patient groups according to their diagnosis than the control group (P < 0.05).
Conclusions
Mean serum homocysteine and plasma vitamin B12 levels were significantly higher in the patient group than the control group (P = 0.002 and 0.000 respectively). There was no significant difference in the levels of folic acid between the patient and control groups. Mean serum B12 values of the AMI and ICD groups in the patient group were significantly lower than those of the control group (P < 0.05). Serum folic acid values of the PAE and AMI groups were considerably lower than the control group (P < 0.05). Plasma homocysteine levels were significantly higher in all patient groups according to their diagnosis than the control group (P < 0.05).
References
Cattaneo M: Semin Thromb Hemost. 2006, 32: 716-723. 10.1055/s-2006-951456
Ho CH, et al.: J Chin Med Assoc. 2005, 68: 560-565. 10.1016/S1726-4901(09)70094-2
Author information
Authors and Affiliations
Rights and permissions
This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
About this article
Cite this article
Bayır, A., Karabulut, K.U. & Ak, A. Levels of serum B12, folic acid and homocysteine in thromboembolic diseases on admission to the Emergency Department. Crit Care 15 (Suppl 1), P14 (2011). https://doi.org/10.1186/cc9434
Published:
DOI: https://doi.org/10.1186/cc9434
Keywords
- Patient Group
- Folic Acid
- Pulmonary Embolism
- Homocysteine
- Deep Vein Thrombosis