Table 1 Hemodynamic and acid-base measurements
Control saline group (n= 5) | Control NaHS group (n= 5) | HS saline group (n= 11) | HS NaHS group (n= 11) | |
|---|---|---|---|---|
MAP (mmHg) | ||||
Baseline | 145 ± 8 | 147 ± 16 | 146 ± 13 | 140 ± 12 |
Reperfusion | 128 ± 18 | 128 ± 18 | 131 ± 16 | 135 ± 14 |
End experiment | 119 ± 20 | 126 ± 8 | 65 ± 32§ | 101 ± 16.5*§ |
HR (beat/min) | ||||
Baseline | 414 ± 25 | 402 ± 55 | 406 ± 45 | 414 ± 40 |
Reperfusion | 408 ± 34 | 408 ± 34 | 420 ± 43 | 398 ± 45 |
End experiment | 414 ± 25 | 426 ± 33 | 429 ± 45 | 423 ± 57 |
CBF (ml/min) | ||||
Baseline | 5.4 ± 1.1 | 5.5 ± 2.3 | 7.1 ± 2.7 | 7.2 ± 2.3 |
Reperfusion | 4.8 ± 0.7 | 6.3 ± 3.5 | 6.5 ± 2.9 | 8.4 ± 3.5 |
End experiment | 4.1 ± 1.4 | 7.1 ± 3.9 | 1.86 ± 1.6§ | 4.4 ± 1.9*§ |
pH | ||||
Baseline | 7.41 ± 0.04 | 7.40 ± 0.09 | 7.34 ± 0.05 | 7.35 ± 0.03 |
Reperfusion | 7.42 ± 0.04 | 7.38 ± 0.08 | 7.23 ± 0.12 | 7.22 ± 0.10 |
End experiment | 7.40 ± 0.08 | 7.41 ± 0.04 | 7.27 ± 0.11 | 7.34 ± 0.09*§ |
Base excess (mM) | ||||
Baseline | 4.56 ± 1.55 | 3.76 ± 1.30 | 2.41 ± 1.69 | 2.98 ± 1.71 |
Reperfusion | 4.96 ± 2.16 | 2.82 ± 1.79 | -7.24 ± 6.7 | -3.28 ± 3.24 |
End experiment | 2.60 ± 1.86 | 2.14 ± 2.74 | -7.61 ± 7.23 | -2.17 ± 3.58* |