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Figure 1 | Critical Care

Figure 1

From: Human protein C concentrate in the treatment of purpura fulminans: a retrospective analysis of safety and outcome in 94 pediatric patients

Figure 1

Flow of patients through the study and exclusions of patients. The diagnosis of purpura fulminans (PF) was regarded as definite in the presence of livid to partly necrotic lesions of irregular shape and with sharp, clearly defined borders with either rapid progression or already ubiquitous appearance. The diagnosis of PF was regarded as probable in the presence of livid to partly necrotic lesions of irregular shape and with sharp, clearly defined borders. The diagnosis of PF was regarded as unclear in the presence of just livid to partly necrotic lesions without any of the other criteria. The diagnosis of PF was not confirmed in any patient with lesions not fulfilling the above defined criteria. PC, protein C.

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