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Table 2 The predictive value of estimated dead-space fraction at day 1 and day 3 of ALI/ARDS in the Mayo validation cohort, outcome hospital mortality

From: Bedside quantification of dead-space fraction using routine clinical data in patients with acute lung injury: secondary analysis of two prospective trials

Mortality Odds ratio 95% CI
Day 1    
(Per 0.05 increment of dead space fraction)    
Univariate analysis
VdVt 1.33 1.09 1.69
Multivariate analysis
Base model (Shock + APACHE III predicted mortality), n= 108 1.28 1.04 1.64
Base model + PaO2/FiO2, n = 108 1.26 1.08 1.61
Base model + OI, n = 107 1.25 1.02 1.61
Base model + PaO2/FiO2 + PEEP, n = 108 1.26 1.08 1.64
Base model + PaO2/FiO2 + PEEP, n = 107 1.29 1.02 1.69
Base model + Vt, n = 108 1.32 1.05 1.70
Day 3    
(Per 0.05 increment of dead space fraction)    
Univariate analysis
VdVt 1.47 1.18 1.90
Multivariate analysis
Base Model (Shock + APACHE III predicted mortality), n = 108 1.43 1.13 1.87
Base model + PaO2/FiO2, n = 108 1.35 1.05 1.78
Base model + OI, n = 85 1.43 1.03 2.11
Base model + PaO2/FiO2 + PEEP, n = 108 1.35 1.05 1.79
Base model + PaO2/FiO2 + PEEP, n = 85 1.43 1.03 2.12
Base model + Vt, n = 108 1.47 1.14 1.96
  1. ALI, acute lung injury; APACHE, acute physiology and chronic health evaluation; ARDS, acute respiratory distress syndrome; CI, confidence interval; FiO2, fraction of inspired oxygen; PaO2, partial pressureof arterial pressure; PEEP, positive end-expiratory pressure; OI, oxygenation index; VdVt, dead space fraction; Vt, tidal volume.