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Table 3 Prediction of sepsis diagnosis on admission: univariate regression analyse* (n = 74 patients)

From: Proven infection-related sepsis induces a differential stress response early after ICU admission

  Odds Ratio (OR)
(lower to upper 95% CI)
P-value
Cortisol baseline ≥ 450 nM/L 5.120 (1.623 to 16.156) 0.004
Apache II score ≥ 14 4.895 (1.652 to 14.503) 0.003
Shock 5.454 (1.841 to 16.159) 0.001
Sepsis score >7 6.48 (2.34 to 17.952) 0.0002
ACTH ≤ 233 nM/L 7.041 (2.446 to 20.271) 0.0001
Procalcitonin (PCT) >2 ng/ml 16.889 (3.523 to 80.959) 0.0001
At least two out of: cortisol, ACTH, sepsis score † 19.200 (5.741 to 64.210) < 0.0001
At least two out of: cortisol, ACTH, PCT † 31.071 (8.215 to 117.516) < 0.0001
  1. ACTH, adreno corticotropic hormone; CI, confidence interval; OR, odds ratio; PCT, procalcitonin.
  2. *: only significant factors are expressed (P < 0.05).
  3. †: according to individual cut-offs values.