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Table 3 Prediction of sepsis diagnosis on admission: univariate regression analyse* (n = 74 patients)

From: Proven infection-related sepsis induces a differential stress response early after ICU admission

 

Odds Ratio (OR)

(lower to upper 95% CI)

P-value

Cortisol baseline ≥ 450 nM/L

5.120 (1.623 to 16.156)

0.004

Apache II score ≥ 14

4.895 (1.652 to 14.503)

0.003

Shock

5.454 (1.841 to 16.159)

0.001

Sepsis score >7

6.48 (2.34 to 17.952)

0.0002

ACTH ≤ 233 nM/L

7.041 (2.446 to 20.271)

0.0001

Procalcitonin (PCT) >2 ng/ml

16.889 (3.523 to 80.959)

0.0001

At least two out of: cortisol, ACTH, sepsis score †

19.200 (5.741 to 64.210)

< 0.0001

At least two out of: cortisol, ACTH, PCT †

31.071 (8.215 to 117.516)

< 0.0001

  1. ACTH, adreno corticotropic hormone; CI, confidence interval; OR, odds ratio; PCT, procalcitonin.
  2. *: only significant factors are expressed (P < 0.05).
  3. †: according to individual cut-offs values.