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Table 2 Time changes in pulmonary hemodynamics and ventilatory pressures

From: Time course of nitric oxide synthases, nitrosative stress, and poly(ADP ribosylation) in an ovine sepsis model

   Time after injury (hours)
  Control 4 8 12 18 24
MPAP, mmHg 24 ± 2 24 ± 2 28 ± 3 26 ± 2 31 ± 3 28 ± 2
PVR, mmHg 186 ± 25 134 ± 24 156 ± 22 150 ± 14 180 ± 29 145 ± 11
PCWP, mmHg 12 ± 1 15 ± 1 18 ± 1a 14 ± 1 16 ± 1 19 ± 2b
Ppeak, cmH2O 20 ± 1 21 ± 2 24 ± 4 22 ± 3 30 ± 2a 31 ± 2a
Ppause, cmH2O 16 ± 1 19 ± 2 22 ± 3 20 ± 3 25 ± 2a 25 ± 3a
  1. Values recorded before sacrifice of animals with sham injury (control) and at different time points after induction of sepsis following acute lung injury. Each group includes four animals.
  2. MPAP, mean pulmonary arterial pressure; PCWP, pulmonary capillary wedge pressure; Ppeak, peak airway pressure; Ppause, pause airway pressure; PVR, pulmonary vascular resistance. a P < 0.05, b P < 0.01.