|  | Time after injury (hours) | ||||
---|---|---|---|---|---|---|
 | Control | 4 | 8 | 12 | 18 | 24 |
MAP, mmHg | 105 ± 1 | 108 ± 10 | 87 ± 4a | 81 ± 4a | 76 ± 11b | 63 ± 2c |
CO, L/min | 3.8 ± 0.2 | 5.4 ± 0.4 | 5.4 ± 0.1 | 6.6 ± 0.6a | 6.9 ± 0.5a | 7.1 ± 0.3b |
apH, -log10 [H+] | 7.50 ± 0.02 | 7.60 ± 0.03 | 7.50 ± 0.07 | 7.51 ± 0.02 | 7.37 ± 0.04a | 7.29 ± 0.06a |
aBE, mmol/L | 2.1 ± 0.8 | 3.9 ± 1.9 | -0.4 ± 2.0 | 0.3 ± 1.3 | -3.2 ± 1.8 | -3.6 ± 2.0a |
PaCO2, mmHg | 31 ± 0.0 | 30 ± 2 | 32 ± 4 | 30 ± 1 | 34 ± 2 | 38 ± 3a |
BCT, °C | 39.6 ± 0.1 | 40.7 ± 0.7 | 41.0 ± 0.2 | 40.6 ± 0.1a | 40.1 ± 0.4a | 39.2 ± 0.5 |
WBC, K/μL | 6.7 ± 1.4 | 3.2 ± 1.0a | 1.8 ± 0.6b | 2.2 ± 0.6b | 1.8 ± 0.5b | 1.1 ± 0.2c |