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Table 7 Platelet values over time with actual and percent change from baseline by treatment

From: A multi-center, randomized, double-blind, parallel, placebo-controlled trial to evaluate the efficacy, safety, and pharmacokinetics of intravenous ibuprofen for the treatment of fever in critically ill and non-critically ill adults

Platelets (×109/L) Lab values over time Change from baseline (actual and percent)
  Baseline Hour 24 Hour 72 Hour 120 to Hour 24 to Hour 72 to Hour 120
100 mg IV Ibuprofen Average 222 210 270 325 -14 -7% 40 41% 112 109%
  SD 159 164 157 191 43 17 92 69 145 140
  N 31 30 28 27 30 30 28 28 27 27
  Min 41 36 73 39 -99 -41% -191 -38% -169 -77%
  Max 659 756 690 933 103 20% 230 269% 473 513%
200 mg IV Ibuprofen Average 190 201 293 416 11 7% 101 82% 228 188%
  SD 111 127 190 239 63 27 148 99 194 180
  N 30 30 26 24 30 30 26 26 24 24
  Min 35 29 102 148 -197 -56% -200 -57% 3 2%
  Max 477 492 965 1258 205 71% 678 412% 971 686%
400 mg IV Ibuprofen Average 174 162 229 308 -9 -6% 55 54% 136 156%
  SD 116 110 126 149 36 23 103 69 168 161
  N 31 30 31 27 30 30 31 31 27 27
  Min 34 20 39 117 -87 -49% -209 -41% -301 -58%
  Max 516 464 562 866 115 64% 367 243% 685 533%
Placebo Average 220 213 268 339 -7 -4% 43 32% 127 98%
  SD 124 136 137 137 61 28 84 56 114 122
  N 28 28 27 24 28 28 27 27 24 24
  Min 48 5 22 61 -163 -97% -192 -87% -162 -64%
  Max 541 448 502 594 130 44% 178 213% 301 521%