Table 5 Creatinine values over time with actual and percent change from baseline by treatment
Creatinine (mg/dL) | Lab values over time | Change from baseline (actual and percent) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Baseline | Hour 24 | Hour 72 | Hour 120 | to Hour 24 | to Hour 72 | to Hour 120 | |||||
100 mg IV Ibuprofen | Average | 0.95 | 0.85 | 0.85 | 0.87 | -.009 | -6.4% | -0.09 | -4.1% | -0.08 | -1.9% |
SD | 0.26 | 0.21 | 0.21 | 0.30 | 0.23 | 25.6 | 0.33 | 37.0 | 0.40 | 48.7 | |
N | 31 | 30 | 29 | 28 | 30 | 30 | 29 | 29 | 28 | 28 | |
Min | 0.57 | 0.50 | 0.50 | 0.50 | -0.60 | -44.4% | -0.80 | -50.0% | -0.90 | -56.3% | |
Max | 1.60 | 1.40 | 1.70 | 2.20 | 0.50 | 71.4% | 1.00 | 142.9% | 1.50 | 214.3% | |
200 mg IV Ibuprofen | Average | 0.97 | 0.85 | 0.90 | 0.83 | -0.12 | -11.4% | -0.07 | -6.0% | -0.08 | -7.5% |
SD | 0.25 | 0.28 | 0.29 | 0.19 | 0.20 | 18.3 | 0.23 | 19.5 | 0.17 | 18.7 | |
N | 30 | 30 | 27 | 24 | 30 | 30 | 27 | 27 | 24 | 24 | |
Min | 0.60 | 0.11 | 0.50 | 0.50 | -0.97 | -89.8% | -0.60 | -37.5% | -0.40 | -28.6% | |
Max | 1.60 | 1.50 | 1.70 | 1.30 | 0.20 | 15.4% | 0.50 | 41.7% | 0.30 | 50.0% | |
400 mg IV Ibuprofen | Average | 0.97 | 0.97 | 1.07 | 1.05 | 0.00 | -2.8% | 0.11 | 6.7% | 0.06 | 5.8% |
SD | 0.35 | 0.59 | 1.05 | 0.93 | 0.37 | 31.7 | 0.93 | 88.7 | 0.86 | 84.5 | |
N | 31 | 30 | 31 | 27 | 30 | 30 | 31 | 31 | 27 | 27 | |
Min | 0.40 | 0.30 | 0.30 | 0.30 | -0.31 | -34.1% | -0.30 | -30.0% | -0.40 | -33.3% | |
Max | 2.10 | 3.20 | 5.81 | 5.28 | 1.39 | 136.3% | 4.79 | 469.6% | 4.26 | 417.6% | |
Placebo | Average | 1.00 | 0.94 | 0.86 | 0.87 | -0.06 | -5.4% | -0.14 | -10.3% | -0.16 | -9.8% |
SD | 0.44 | 0.40 | 0.25 | 0.23 | 0.13 | 12.4 | 0.26 | 15.5 | 0.34 | 20.4 | |
N | 28 | 28 | 28 | 24 | 28 | 28 | 28 | 28 | 24 | 24 | |
Min | 0.60 | 0.42 | 0.50 | 0.50 | -0.30 | -33.3% | -1.10 | -46.7% | -1.30 | -53.3% | |
Max | 2.80 | 2.50 | 1.70 | 1.50 | 0.20 | 18.2% | 0.20 | 25.0% | 0.30 | 37.5% | |