Table 3 Outcomes
From: Early fluid resuscitation with hyperoncotic hydroxyethyl starch 200/0.5 (10%) in severe burn injury
Outcome | Baxter group (n = 14) | HES group (n = 16) | Adjusted hazard ratio or mean difference (95% CI, P value)# | ||
|---|---|---|---|---|---|
Mortality | Overall mortality (%) | 2 (14.3) | 7 (43.8) | Hazard ratio: 7.12 (0.45-112.7, P = 0.16) | |
Renal parameters | Continuous renal replacement therapy (%) | 1 (7.1) | 4 (25.0) | Hazard ratio: 6.16 (0.07-505.7, P = 0.42) | |
Creatinine clearance | 24 hours | 125.9 (20.1) | 102.5 (38.8) | Mean difference: -6.5 (-26.8 to 13.7, P = 0.51) | |
48 hours | 125.9 (25.6) | 95.6 (40.3) | Mean difference: -14.7 (-37.8 to 8.4, P = 0.20 | ||
72 hours | 124.2 (33.4) | 97.4 (47.2) | Mean difference: -4.8 (-28.3 to 18.6, P = 0.67) | ||
Urinary output | 72 hours | 165.1 (53.1) | 135.8 (59.3) | Mean difference: -9.7 (-56.6 to 37.2, P = 0.67) | |
Pulmonary parameters | ARDS (%) | 4 (28.6) | 3 (18.8) | Hazard ratio: 1.26 (0.14-11.35, P = 0.84) | |
Ventilator days | 7.4 (11.0) | 12.3 (19.7) | Mean difference: -2.4 (-12.9 to 8.2, P = 0.65) | ||
Horowitz | 72 hours | 237.2 (98.3) | 225.4 (85.7) | Mean difference: 17.5 (-51.7 to 86.6, P = 0.61) | |
Surgical parameters | Beginning of surgical treatment within first 3 days (%) | 10 (71.4) | 9 (56.3) | Hazard ratio: 2.00 (0.58-6.93, P = 0.27) | |
Time to complete surgical coverage (days) | 23.0 (15.7) | 31.9 (30.8) | Mean difference: 1.7 (-25.2 to 28.6, P = 0.89) | ||
Other parameters | Sepsis (%) | 5 (35.7) | 6 (37.5) | Hazard ratio: 0.95 (0.16-5.56, P = 0.95) | |
Hospital days | 32.4 (16.1) | 28.6 (20.7) | Mean difference: -6.7 (-22.9 to 9.6, P = 0.40) | ||
ICU days | 27.0 (14.1) | 23.6 (17.4) | Mean difference: -7.6 (-21.1 to 5.8, P = 0.25) | ||