Table 1 Demographic and clinical characteristics of patients enrolled in the study

Total number

183

97

100

61

64

Male/female

86/97

61/36

51/39

41/20

41/23

0.011

Age (years, mean ± SD)

67.3 ± 17.1

68.4 ± 19.7

54.1 ± 24.5

64.0 ± 16.3

70.6 ± 14.5

<0.0001

APACHE II (mean ± SD)

11.7 ± 6.8

15.7 ± 8.8

12.7 ± 7.7

18.2 ± 7.5

20.0 ± 5.4

<0.0001

White blood cells (/μl, mean ± SD)

15684.3 ± 11481.3

15002.2 ± 7272.8

15595.7 ± 7027.8

13755.9 ± 9551.8

13905.7 ± 8289.2

NS

Sepsis/severe sepsis-shock

141/42

56/41

70/30

23/38

22/42

<0.0001

Death (number, %)

14 (7.7)

30 (30.9)

16 (16.0)

21 (34.4)

22 (34.4)

<0.0001

Pathogen* (number, %)

0.039

71 (38.7)

-

3 (3.0)

12 (19.7)

0 (0)

18 (9.8)

-

3 (3.0)

20 (32.8)

15 (23.5)

12 (6.6)

-

2 (2.0)

12 (19.7)

0 (0)

3 (1.6)

-

0 (0)

10 (16.3)

14 (21.9)

9 (4.9)

-

0 (0)

7 (11.5)

1 (1.6)

6 (3.3)

1 (1.6)

5 (2.7)

7 (7.2)

2 (2.0)

4 (6.5)

0 (0)

Co-morbidities (number, %)

0.045

48 (26.2)

19 (19.6)

19 (19.0)

16 (26.2)

14 (21.9)

23 (12.6)

14 (14.4)

9 (9.0)

13 (21.3)

11 (17.2)

15 (8.2)

20 (20.6)

5 (5.0)

8 (13.1)

9 (14.1)

17 (9.3)

6 (6.2)

3 (3.0)

8 (13.1)

7 (10.9)