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Table 4 Change in angiopoietin-2 and other variables over time

From: Angiopoietin-2 is increased in sepsis and inversely associated with nitric oxide-dependent microvascular reactivity

  Day 0 Day 2-4 P valuea
RH-PAT b 1.67 (1.55-1.78) 1.83 (1.67-1.99) NS
SOFA score c 4 (2-8) 3 (1-7) 0.07
Ang-2 (ng/ml) c 10.16 (5.32-19.39) 8.72 (5.38-15.73) 0.01
VEGF (pg/ml) c 94.8 (57.0-143.8) 73.6 (48.6-167.3) NS
ICAM-1 (ng/ml) c 655.6 (448.0-1084.1) 694.0 (450.3-1258.1) NS
E-selectin (ng/ml) c 154.5 (69.1-396.3) 120.3 (63.9-199.2) <0.0001
IL-6 (pg/ml) c 224.4 (75.0-595.5) 58.1 (17.2-255.8) <0.0001
  1. a. Mean (95% confidence interval).
  2. b. Median (Interquartile range).
  3. c. Wilcoxon's paired signrank test.
  4. Ang-2, angiopoietin-2; ICAM-1, intra-cellular adhesion molecule-1; IL-6, interleukin 6; NS, not significant; RH-PAT, reactive hyperemia peripheral arterial tonometry; SOFA, Sequential Organ Failure Assessment score; VEGF, vascular endothelial growth factor.