Pooled IGF-I concentrations in patients with aSAH and in the control group. The line represents the cut-off level of 11 nmol/l. The insulin like growth factor-I (IGF-I) concentration was below 11 nmol/l on day one in 77% of aneurysmal subarachnoid hemorrhage (aSAH) patients and in 23% (P = 0.02) of control patients. The respective values were 74% and 27% (P = 0.05) on day two, 70% and 30% (P = 0.3) on day three, 72% and 28% (P = 0.22) on day four, and 74% and 27% (P = 0.05) on day five. In the aSAH group, 83% of patients on day six and 76% on day seven had IGF-concentrations below 11 nmol/l. At three months, no patient had IGF-concentrations lower than 11 nmol/l.