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Table 1 Baseline characteristics and neurological outcome of patients treated with mild therapeutic hypothermia (MTH) and non-hypothermia (NH) group

From: Mild therapeutic hypothermia alters neuron specific enolase as an outcome predictor after resuscitation: 97 prospective hypothermia patients compared to 133 historical non-hypothermia patients

  NH MTH P-value
  (n = 133) (n = 97)  
Baseline parameters    
Age (years) 64.3 (52.9 to 73.0) 60.3 (51.5 to 70.0) 0.123
Gender    
   female 33 (24.8) 21 (21.6) 0.638
   male 100 (75.2) 76 (78.4)  
APACHE II score 26.0 (20.0 to 32.0) 31.0 (24.0 to 34.0) 0.003
Cardiac arrest    
   Out-of-hospital 101 (75.9) 81 (83.5) 0.190
   In-hospital 32 (24) 16 (16.5)  
Cardiac rhythm    
   Shockable rhythm 73 (54.9) 65 (67.0) 0.077
   Non-shockable rhythm 60 (45.1) 32 (33.0)  
Cause of cardiac arrest    
   AMI 82 (61.7) 55 (56.7) 0.688
   Primary arrhythmia 24 (18) 22 (22.7)  
   Respiratory 22 (16.5) 18 (18.6)  
   Other 5 (3.8) 2 (2.1)  
Bystander CPR    
   yes 24 (18.0) 38 (39.2) <0.001
   No 109 (82.0) 59 (60.8)  
Time to ROSC (minutes) 22 (14 to 30) 20 (12 to 27) 0.176
Total epinephrine dose (mg) 3.0 (2.0 to 5.0) 3.0 (1.0 to 4.5) 0.039
Length of ICU stay (days) 15 (7 to 26) 13 (7 to 23) 0.693
Neurological Outcome    
CPC at ICU discharge    
   1 - good recovery 16 (12) 33 (34) <0.001
   2 - moderate disability 14 (10.5) 20 (20.6)  
   3 - severe disability 5 (3.8) 5 (5.2)  
   4 - vegetative state 34 (25.6) 5 (5.2)  
   5 - death 64 (48.1) 34 (35.1)  
  1. Data are presented as median (25th to 75th percentiles) or as absolute numbers (%). CPR, cardiopulmonary resuscitation, ROSC, return of spontaneous circulation, CPC, cerebral performance category, NSE, neuron specific enolase, AMI, acute myocardial infarction, APACHE, Acute Physiology and Chronic Health Evaluation