Table 1 Baseline characteristics and neurological outcome of patients treated with mild therapeutic hypothermia (MTH) and non-hypothermia (NH) group
NH | MTH | P-value | |
|---|---|---|---|
(n = 133) | (n = 97) | ||
Baseline parameters | |||
Age (years) | 64.3 (52.9 to 73.0) | 60.3 (51.5 to 70.0) | 0.123 |
Gender | |||
female | 33 (24.8) | 21 (21.6) | 0.638 |
male | 100 (75.2) | 76 (78.4) | |
APACHE II score | 26.0 (20.0 to 32.0) | 31.0 (24.0 to 34.0) | 0.003 |
Cardiac arrest | |||
Out-of-hospital | 101 (75.9) | 81 (83.5) | 0.190 |
In-hospital | 32 (24) | 16 (16.5) | |
Cardiac rhythm | |||
Shockable rhythm | 73 (54.9) | 65 (67.0) | 0.077 |
Non-shockable rhythm | 60 (45.1) | 32 (33.0) | |
Cause of cardiac arrest | |||
AMI | 82 (61.7) | 55 (56.7) | 0.688 |
Primary arrhythmia | 24 (18) | 22 (22.7) | |
Respiratory | 22 (16.5) | 18 (18.6) | |
Other | 5 (3.8) | 2 (2.1) | |
Bystander CPR | |||
yes | 24 (18.0) | 38 (39.2) | <0.001 |
No | 109 (82.0) | 59 (60.8) | |
Time to ROSC (minutes) | 22 (14 to 30) | 20 (12 to 27) | 0.176 |
Total epinephrine dose (mg) | 3.0 (2.0 to 5.0) | 3.0 (1.0 to 4.5) | 0.039 |
Length of ICU stay (days) | 15 (7 to 26) | 13 (7 to 23) | 0.693 |
Neurological Outcome | |||
CPC at ICU discharge | |||
1 - good recovery | 16 (12) | 33 (34) | <0.001 |
2 - moderate disability | 14 (10.5) | 20 (20.6) | |
3 - severe disability | 5 (3.8) | 5 (5.2) | |
4 - vegetative state | 34 (25.6) | 5 (5.2) | |
5 - death | 64 (48.1) | 34 (35.1) |