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Table 7 Factors associated with adequate management

From: Febrile neutropenia in French emergency departments: results of a prospective multicentre survey

Variables

 

Adequate management

(n = 33)

Inadequate management

(n = 161)

P

Tertiary teaching hospital

Yes

24 (12)

92 (88)

0.1

 

No

9 (21)

68 (79)

 

Number of ED visits during study period

<20 000

17 (18)

78 (82)

0.80

 

≥ 20 000

15 (16)

76 (84)

 

Unit for cancer patients

Yes

29 (18)

132 (82)

1

 

No

4 (15)

22 (85)

 

Written procedures for febrile neutropenia management

Yes

24 (21)

92 (79)

0.16

 

No

9 (13)

62 (87)

 

Age (mean ± SD)

 

58 ± 17

61 ± 14

0.30

Sex

Male

17 (15)

97 (85)

0.29

 

Female

16 (21)

61 (79)

 

Karnosfsky index (median (range))

 

70 (30-100)

80 (30-100)

0.07

Place of stay

Home

30 (18)

139 (82)

0.23

 

House care

2 (40)

3 (60)

 

Underlying disorder

Yes

12 (17)

60 (83)

0.78

 

No

21 (18)

94 (82)

 

Type of cancer

Haematological

14 (17)

70 (83)

0.91

 

Solid cancer

19 (17)

91 (83)

 

Presence of metastasis or uncontrolled

Yes

22 (17)

108 (83)

0.96

 

No

11 (17)

53 (83)

 

Antimicrobial therapy prior to ED

Yes

9 (9)

39 (91)

0.75

 

No

24 (17)

119 (83)

 

Time of ED visit

Day

18 (15)

102 (85)

0.24

 

Night

15 (22)

54 (78)

 

Level of nurse triage

<3

20 (22)

73 (78)

0.43

 

≥ 3

8 (16)

42 (84)

 

Presence of severity signs according to ED physician

Yes

9 (17)

45 (83)

0.82

 

No

24 (18)

109 (82)

 

Severe sepsis

Yes

6 (7)

80 (93)

0.0009

 

No

27 (25)

81 (75)

 

Cancer specialist advice

Yes

14 (17)

70 (83)

0.95

 

No

18 (17)

88 (83)

 

MASCC classification

High risk

32 (31)

71 (69)

<0.001

 

Low risk

1 (1)

90 (99)

 

Protective isolation

Yes

29 (19)

128 (81)

0.50

 

No

4 (13)

26 (87)

 

Surgical management

Yes

2 (50)

2 (50)

0.12

 

No

26 (15)

146 (85)

 

Adequate orientation

Agree

26 (17)

129 (83)

0.65

 

Disagree

7 (20)

28 (80)

 
  1. Values shown are number and percentage unless stated otherwise. P values below 0.05 are statistically significant.
  2. ED, emergency department; G-CSF, granulocyte-cell stimulating factor; MASCC, Multinational Association for Supportive Care in Cancer; SD, standard deviation.