Table 1 Patients, surgical procedure and survey characteristics, and levels of IL-6, CRP and cortisol on postoperative Day 1 (POD1)
From: Differential down-regulation of HLA-DR on monocyte subpopulations during systemic inflammation
| Â | AAS patients (n = 20) | CAS patients (n = 20) | P-value |
|---|---|---|---|
Age (years) | 67.0 ± 2.9 | 73.9 ± 2.8 | ns |
Male/female (n) | 17/3 | 13/7 | ns |
Blood loss (mL) | 1,000 (400-3,500) | 100 (50-900) | < 10-4 |
Fluid infusion (mL) | 4,500 (3,000-9,000) | 1,500 (1,000-3,000) | < 10-4 |
Red blood cell transfusion | 1 (0 to 6) | 0 (0 to 2) | < 10-4 |
Fresh-frozen plasma | 1 (0 to 4) | 0 | ns |
Cell-saver | 2 (0 to 8) | 0 | ns |
Operation duration (hours) | 2.5 (1.6 to 6.5) | 1.2 (1 to 2.5) | < 10-4 |
Vascular clamping duration (minutes) | 50.5 (14 to 90) | 26 (12 to 45) | < 10-4 |
Post-surgical complications (cardiac and/or respiratory) | 9 | 3 | 0.038 |
Infection | 4 | 2 | ns |
IL-6 pg/ml (POD1) | 142 ± 41 | 14 ± 3 | 0.004 |
CRP pg/ml (POD1) | 132 ± 16 | 25 ± 4 | < 0.001 |
Cortisol ng/ml (POD1) | 229 ± 44 | 157 ± 26 | 0.07 |