Table 3 Predicted cost-utilities in subgroups of patients with acute respiratory failure
n | Gained survival (years) | QALYs (years) | Cost/hospital survivor | Cost/QALY | |
|---|---|---|---|---|---|
mean (SD) | mean (SD) | € | € | ||
Age (years) | |||||
≤ 51 | 252 | 36 (19) | 25 (16) | 19,195 | 670 |
52-63 | 236 | 17 (11) | 11 (8) | 21,069 | 1,582 |
64-74 | 251 | 9 (8) | 6 (6) | 21,499 | 2,620 |
≥ 75 | 219 | 4 (5) | 3 (3) | 21,737 | 5,263 |
SAPS II (points) | |||||
≤ 31 | 253 | 28 (18) | 20 (15) | 15,187 | 726 |
32-43 | 246 | 18 (16) | 11 (12) | 22,545 | 1,656 |
44-55 | 222 | 13 (15) | 8 (11) | 23,565 | 2,026 |
≥ 56 | 237 | 8 (13) | 5 (9) | 24,760 | 2,560 |
Activities of daily life | |||||
Able to work | 482 | 23 (19) | 16 (14) | 19,718 | 1,028 |
Unable to work but needs no help | 337 | 12 (13) | 8 (9) | 21,665 | 2,075 |
Needs some help | 113 | 8 (12) | 5 (9) | 21,512 | 2,722 |
Needs help to activities of daily life | 17 | 8 (15) | 5 (12) | 30,653 | 3,450 |
Admission type | |||||
Elective | 133 | 16 (14) | 12 (12) | 17,273 | 1,283 |
Emergency | 821 | 17 (18) | 11 (13) | 21,462 | 1,410 |
Ventilatory support | |||||
NIV only | 105 | 15 (17) | 11 (14) | 13,154 | 956 |
Invasive ventilation only | 775 | 17 (17) | 12 (13) | 20,065 | 1,313 |
NIV and invasive ventilation before 6 hours | 43 | 11 (16) | 6 (9) | 42,625 | 3,733 |
NIV and invasive ventilation after 6 hours | 35 | 13 (17) | 8 (11) | 44,971 | 3,499 |
Chronic diseases, count | |||||
0 | 425 | 23 (19) | 16 (15) | 19,065 | 966 |
1 | 320 | 13 (15) | 8 (11) | 22,583 | 1,936 |
2 | 158 | 10 (11) | 7 (9) | 21,699 | 2,337 |
3 | 47 | 9 (9) | 6 (6) | 24,400 | 3,102 |
4 | 8 | 8 (9) | 4 (5) | 34,108 | 3,910 |
ARF risk factors 48 hours before | |||||
Sepsis | 136 | 14 (15) | 9 (12) | 37,219 | 2,599 |
Cardiac insufficiency | 192 | 9 (12) | 6 (8) | 27,322 | 2,779 |
Pneumonia | 114 | 14 (16) | 9 (12) | 26,368 | 2,106 |
Post-operative with ventilatory support < 1 day | 132 | 17 (15) | 12 (12) | 11,025 | 836 |