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Table 1 Baseline characteristics of patients

From: Nicotine withdrawal and agitation in ventilated critically ill patients

  Smokers
(n = 44)
Nonsmokers
(n = 100)
P value
Age, yr 54 (45.5-62.5) 69 (58-78.5) <0.0001
Male gender, n (%) 40 (91) 70 (70) 0.006
Medical origin, n (%) 38 (86) 81 (81) 0.5
Source, admission from the ward, n (%) 9 (20) 29 (29) 0.3
Comorbidities, n (%)    
   Hypertension 7 (16) 20 (20) 0.6
   Alcoholism 30 (68) 20 (20) <0.0001
   Psychotropic drug use 15 (34) 25 (25) 0.3
Tobacco dependency    
   Pack-years 28 (22-40) NA  
   Fagerström score 5 (3-6) NA NA
Score ≤4 (Weak dependence), n (%) 20 (45)   
Score >4 (Strong dependence), n (%) 24 (55)   
Primary diagnosis, n (%)    
   Cardiac disease 1 (2) 16 (16)  
   Respiratory disease 15 (34) 41 (41)  
   Septic shock 14 (32) 18 (18) 0.007
   Neurologic disease 6 (14) 7 (7)  
   Surgery 2 (4) 14 (14)  
   Other 6 (14) 8 (8)  
SAPS II 46.5 (39-60) 50 (40.5-63) 0.3
SOFA score 7.5 (5.5-10) 8 (6-10) 0.5
Vasopressor, n (%) 28 (64) 51 (51) 0.2
Body temperature >38.5°C, n (%) 12 (27) 17 (17) 0.2
PaO2/FiO2 222 (165-257) 186 (135-250) 0.1
  1. Abbreviations: NA, not attributable; SAPS II, Simplified Acute Physiology Score II; SOFA, Sequential Organ Failure Assessment. Data are presented as number (percentage) or median (interquartile range).