Table 1 Baseline characteristics of patients
From: Nicotine withdrawal and agitation in ventilated critically ill patients
Smokers (n = 44) | Nonsmokers (n = 100) | P value | |
|---|---|---|---|
Age, yr | 54 (45.5-62.5) | 69 (58-78.5) | <0.0001 |
Male gender, n (%) | 40 (91) | 70 (70) | 0.006 |
Medical origin, n (%) | 38 (86) | 81 (81) | 0.5 |
Source, admission from the ward, n (%) | 9 (20) | 29 (29) | 0.3 |
Comorbidities, n (%) | |||
Hypertension | 7 (16) | 20 (20) | 0.6 |
Alcoholism | 30 (68) | 20 (20) | <0.0001 |
Psychotropic drug use | 15 (34) | 25 (25) | 0.3 |
Tobacco dependency | |||
Pack-years | 28 (22-40) | NA | |
Fagerström score | 5 (3-6) | NA | NA |
Score ≤4 (Weak dependence), n (%) | 20 (45) | ||
Score >4 (Strong dependence), n (%) | 24 (55) | ||
Primary diagnosis, n (%) | |||
Cardiac disease | 1 (2) | 16 (16) | |
Respiratory disease | 15 (34) | 41 (41) | |
Septic shock | 14 (32) | 18 (18) | 0.007 |
Neurologic disease | 6 (14) | 7 (7) | |
Surgery | 2 (4) | 14 (14) | |
Other | 6 (14) | 8 (8) | |
SAPS II | 46.5 (39-60) | 50 (40.5-63) | 0.3 |
SOFA score | 7.5 (5.5-10) | 8 (6-10) | 0.5 |
Vasopressor, n (%) | 28 (64) | 51 (51) | 0.2 |
Body temperature >38.5°C, n (%) | 12 (27) | 17 (17) | 0.2 |
PaO2/FiO2 | 222 (165-257) | 186 (135-250) | 0.1 |