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Table 1 Patient characteristics, hemodynamic and biologic data on admission, and fluid balance during the first 24 hours

From: Revisiting the loading dose of amikacin for patients with severe sepsis and septic shock

Variables Values
Age (years) 63 ± 13
Sex (Male/Female) 50/24
Body Mass Index 24.7 ± 4.6
APACHE II score 21 (16-26)
SOFA score on admission 8 (5-11)
Medical/Surgical 50/24
COPD 14 (19%)
Diabetes 17 (23%)
Heart disease 39 (53%)
Chronic renal insufficiency 7 (9%)
Liver cirrhosis 11 (15%)
Immunosuppressive drugs 25 (34%)
Malignancy 24 (32%)
Community/hospital-acquired infections 22/52
Severe sepsis/septic shock 17/56
Mechanical ventilation 56 (76%)
Acute renal failure 20 (27%)
Vasopressor agents 56 (76%)
ICU stay (days) 14 (5-25)
Overall ICU mortality 27 (37%)
Mean arterial pressure (mmHg) 70 ± 14
Central venous pressure (mmHg) 10 ± 5
pH 7.41 ± 0.12
PaO2/FiO2 ratio 166 [112-227]
PaCO2 (mmHg) 39 ± 12
Lactate (mEq/L) 2.7 [1.7-3.9]
White blood cells (/mm3) 11400 [8600-20400]
Hematocrit (%) 30.4 ± 7.6
Platelets (103/mm3) 175 [86-292]
Bilirubin (mg/dl) 0.9 [0.5-2.0]
Creatinine (mg/dl) 1.7 [1.1-3.1]
C-reactive protein (mg/dl) 17 [10-26]
Creatinine clearance (ml/min) 54 [33-86]
Fluid balance (ml/24 h) 2650 ± 2121
Fluids IN (ml/24 h) 4594 ± 1892
Fluids OUT (ml/24 h) 1944 ± 1621
  1. Data are expressed as counts (percentage), median (IQR), or mean ± SD. APACHE, Acute Physiology and Chronic Health Evaluation; COPD, chronic obstructive pulmonary disease; ICU, intensive care unit; SOFA, Sequential Organ Failure Assessment.