Table 1 Patient characteristics, hemodynamic and biologic data on admission, and fluid balance during the first 24 hours
From: Revisiting the loading dose of amikacin for patients with severe sepsis and septic shock
Variables | Values |
|---|---|
Age (years) | 63 ± 13 |
Sex (Male/Female) | 50/24 |
Body Mass Index | 24.7 ± 4.6 |
APACHE II score | 21 (16-26) |
SOFA score on admission | 8 (5-11) |
Medical/Surgical | 50/24 |
COPD | 14 (19%) |
Diabetes | 17 (23%) |
Heart disease | 39 (53%) |
Chronic renal insufficiency | 7 (9%) |
Liver cirrhosis | 11 (15%) |
Immunosuppressive drugs | 25 (34%) |
Malignancy | 24 (32%) |
Community/hospital-acquired infections | 22/52 |
Severe sepsis/septic shock | 17/56 |
Mechanical ventilation | 56 (76%) |
Acute renal failure | 20 (27%) |
Vasopressor agents | 56 (76%) |
ICU stay (days) | 14 (5-25) |
Overall ICU mortality | 27 (37%) |
Mean arterial pressure (mmHg) | 70 ± 14 |
Central venous pressure (mmHg) | 10 ± 5 |
pH | 7.41 ± 0.12 |
PaO2/FiO2 ratio | 166 [112-227] |
PaCO2 (mmHg) | 39 ± 12 |
Lactate (mEq/L) | 2.7 [1.7-3.9] |
White blood cells (/mm3) | 11400 [8600-20400] |
Hematocrit (%) | 30.4 ± 7.6 |
Platelets (103/mm3) | 175 [86-292] |
Bilirubin (mg/dl) | 0.9 [0.5-2.0] |
Creatinine (mg/dl) | 1.7 [1.1-3.1] |
C-reactive protein (mg/dl) | 17 [10-26] |
Creatinine clearance (ml/min) | 54 [33-86] |
Fluid balance (ml/24 h) | 2650 ± 2121 |
Fluids IN (ml/24 h) | 4594 ± 1892 |
Fluids OUT (ml/24 h) | 1944 ± 1621 |