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Table 3 Hemodynamic parameters in patients with and without sepsis

From: Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial

  Patients with sepsis Patients without sepsis
Hemodynamic variable* EX
(n = 31)
LZ
(n = 31)
P value DEX
(n = 20)
LZ
(n = 19)
P value
Number of days on vasoactive drugs 1 (1) 2 (2) 0.08 1.5 (2.2) 0.3 (0.9) 0.08
Average daily number of vasoactive drugs 1.1 (0.2) 1.6 (0.5) 0.004 1.6 (0.9) 1 (0) 0.2
Ever vasoactive drugs increased 26% 47% 0.08 33% 16% 0.2
Sinus bradycardia (<60 beats/min) 13% 6% 0.4 24% 0% 0.02
Sinus tachycardia (>100 beats/min) 81% 84% 0.7 52% 53% 1
  1. Mean (standard deviation) unless otherwise noted.
  2. DEX, dexmedetomidine; LZ, lorazepam.
  3. *Measured during 120-hour study drug protocol, except for sinus bradycardia and sinus tachycardia, which are measured during entire study.