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Table 1 Respiratory parameters

From: Regional lung aeration and ventilation during pressure support and biphasic positive airway pressure ventilation in experimental lung injury

  Baseline Injury PSV BIPAP+SBmean BIPAP+SBcontrolled BIPAP+SBspont
MV (L/min) 5.1 ± 1.7 4.1 ± 1.7 6.6 ± 1.9 6.2 ± 2.1 2.3 ± 0.9 †,‡ 4.0 ± 2.2 †,‡,§
VT (mL) 347 ± 58 349 ± 61 202 ± 48 129 ± 40 255 ± 103 97 ± 34 †,‡,§
RR (/min) 15 ± 4 14 ± 4 34 ± 11 51 ± 17 9 ± 3 †,‡ 43 ± 17 †,‡,§
Ti/Ttot 0.49 ± 0.01 0.49 ± 0.01 0.33 ± 0.05 -- 0.24 ± 0.08 0.26 ± 0.06 †,‡
Ppeak (cmH2O) 20 ± 2 34 ± 3 * 23 ± 2 -- 24 ± 3 --
Paw mean (cmH2O) 11 ± 1 15 ± 1 * 9 ± 1 9 ± 1 14 ± 2 †,‡ 5 ± 1 †,‡,§
Ppl mean (cmH2O) 3 ± 2 7 ± 2 * 2 ± 1 2 ± 1 6 ± 3 †,‡ 1 ± 1 †,‡,§
PEEPi,dyn (cmH2O) -- -- 1 ± 1 1 ± 1 -- --
PTP (cmH2O.s.min-1) -- -- 7 ± 5 91 ± 54 -- --
P0.1 (cmH2O) -- -- 1 ± 1 3 ± 1 -- --
  1. Values are given as mean ± standard deviation; baseline, before induction of acute lung injury; injury, after induction of acute lung injury. The contributions of spontaneous and controlled breaths to BIPAP+SBmean were weighted by their respective rates (weighted mean). * P < 0.05 vs. Baseline; P < 0.05 vs. PSV; P < 0.05 vs. BIPAP+SBmean; § P < 0.05 vs. BIPAP+SBcontolled.
  2. BIPAP+SBcontrolled, controlled breath cycles during BIPAP+SBmean; BIPAP+SBmean, biphasic positive airway pressure + spontaneous breathing; BIPAP+SBspont, spontaneous breath cycles during BIPAP+SBspont; MV, minute volume; P0.1, airway pressure generated 100 ms after onset of an occluded inspiratory effort; Paw mean, mean airway pressure; PEEPi,dyn, dynamic intrinsic end-expiratory pressure; Ppeak, peak airway pressure; Ppl mean, mean transpulmonary pressure; PSV, pressure support ventilation; PTP, inspiratory esophageal pressure time product; RR, respiratory rate; Ti/Ttot, inspiratory to total respiratory time; VT, tidal volume.