From: Treatment of hypophosphataemia in critically ill patients with a two day dosing regimen
 |  |  | Efficacy | Safety | |||||
---|---|---|---|---|---|---|---|---|---|
 |  |  |  |  |  |  |  | Mean (SD) change in | |
 |  |  | Mean (SD) serum | Patients % successfully | ionised Ca (mmol/l) from | ||||
 |  |  | PO4 (mmol/l) | corrected (≥0.8 mmol/l) | pre-treatment value | ||||
 |  |  | dose 1 | dose 2 | dose 1 | dose 2 | dose 2 | dose 1 | dose 2 |
Serum PO4 (mmol/l) | Dose | N | +24 h | +24 h | +24 h | +24 h | +48 h | +24 h | +24 h |
0.8-0.6 | 20:20 | 35 | 0.9(0.2) | 1.1(0.4) | 66% | 71% | 74% | -0.06(0.11) | -0.07(0.17) |
0.6-0.4 | 40:20 | 13 | 0.8(0.2) | 0.8(0.2) | 46% | 53% | 69% | +0.03(0.16) | -0.04(0.12) |
<0.4 | 50:20 | 4 | 0.8(0.2) | 0.9(0.3) | 25% | 75% | 75% | -0.02(0.03) | +0.01(0.05) |