Relative hyperlactatemia and hospital mortality in critically ill patients: a retrospective multi-centre study

Table 1 Clinical characteristics of hospital survivors and non-survivors

	n	Hospital Non-survivors	n	Hospital Survivors	P-value
Male Sex	1,561	57.3% (894)	5,590	60.2% (3,365)	0.035
APACHE II score	1,250	24.6 (8.1)	4,845	15.1 (6.6)	< 0.0001
Age (yr)	1,428	65.8 (16.6)	5,181	59.7 (18.9)	< 0.0001
Number on mechanical ventilation	1,434	81.2% (1164)	5,515	55.6% (3,066)	< 0.0001
Surgical patients	1,565	28.4% (444)	5,590	48.7% (2,722)	< 0.0001
Diagnosis at admission
Cardiac and vascular	1,565	26% (407)	5,590	21.6% (1,207)	0.0003
Thoracic and respiratory	1,565	18.5% (290)	5,590	18.9% (1,057)	0.69
Trauma	1,565	2.2% (34)	5,590	7.9% (442)	< 0.0001
Neurological	1,565	14.1% (221)	5,590	10.9% (609)	0.0004
Gastrointestinal tract diseases	1,565	14.1% (221)	5,590	22.9% (1,280)	< 0.0001
Other	1,565	25% (391)	5,590	17.7% (989)	< 0.0001
ICU stay (days)	1,559	3.0 (1.5 to 6.6)	5,589	2.5 (1.6 to 4.9)	< 0.0001
Hospital stay (days)	1,312	9 (3 to 24)	5,131	14 (8 to 29)	< 0.0001
Admission blood lactate (mmom.L ^-1 )	1,395	2.3 (1.4 to 4.4)	5,037	1.5 (1.0 to 2.4)	< 0.0001
Time-weighted blood lactate (mmom.L ^-1)	1,411	2.0 (1.4 to 3.3)	4,977	1.3 (1.0 to 1.8	< 0.0001
Max blood lactate (mmom.L ^-1)	1,565	4.0 (2.2 to 7.5)	5,590	2.1 (1.4 to 3.3)	< 0.0001

Data are expressed as, percentage (number), (standard deviation) or median (interquartile range).
APACHE II, Acute Physiology and Chronic Health Evaluation II.

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