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Figure 5 | Critical Care

Figure 5

From: The relationship between CD4+CD25+CD127- regulatory T cells and inflammatory response and outcome during shock states

Figure 5

Sepsis increases Tregs percentage in mice. Twenty-four hours after caecal ligation and puncture (CLP), proportion of regulatory T lymphocytes (Treg) cells among splenocytes (CD4+CD25+Foxp3+ cells) is determined (n = 6 per group) (a). In some experiments, Tregs were depleted by using anti-CD25 antibody prior to sepsis induction. Depletion was highly effective with less than 1% of Tregs remaining 24 hours after the (b, B) last antibody injection as compared with (b, A) control animals.

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Critical Care

ISSN: 1364-8535