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Table 4 Correlation of SNPs in the mbl2 gene with the serum MBL level

From: Association of mannose-binding lectin-2 genotype and serum levels with prognosis of sepsis

   

Normal control

Severe sepsis

Septic shock

Loci

Allele

Genotype

Median

(IQR)

μg/L

P a

Median

(IQR)

μg/L

P a

Median

(IQR)

μg/L

P a

-550

H

GG

2493

(1452--3992)

0.000

2250

(1285--4800)

0.000

2550

(2010--3945)

0.000

  

GC

955

(335--2626)

 

810

(600--1360)

 

1530bc

(860--2400)

 
 

L

CC

384

(0--1284)

 

340

(275--710)

 

640c

(300--1630)

 

Gly54

Asp

A

GG

2249

(1333--3352)

0.000

1370

(825--3925)

0.000

2280

(1500--2800)

0.000

  

GA

315

(3--540)

 

460b

(335--695)

 

475b

(298--695)

 
 

B

AA

0

 

270

(135-280)

 

270

 

+4

P

CC

1039

(215--2668)

0.036

800

(430--1363)

0.367

1910bc

(1045--2635)

0.470

  

CT

2182

(1187--2826)

 

800

(370--4265)

 

1605

(488--3013)

 
 

Q

TT

4823

 

2895

(830--4960)

 

3570

 
  1. Data are expressed as the median and interquartile range (IQR; 25% to 75%). a = P-value based on the Kruskal--Wallis or Mann--Whitney U test. Statistical differences in the mannose-binding lectin (MBL) levels were analyzed according to genotype within each subgroup. b = P < 0.05 vs. the control group. c = P < 0.05 vs. the severe sepsis group. SNP = single nucleotide polymorphism.