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Table 4 Correlation of SNPs in the mbl2 gene with the serum MBL level

From: Association of mannose-binding lectin-2 genotype and serum levels with prognosis of sepsis

    Normal control Severe sepsis Septic shock
Loci Allele Genotype Median
(IQR)
μg/L
P a Median
(IQR)
μg/L
P a Median
(IQR)
μg/L
P a
-550 H GG 2493
(1452--3992)
0.000 2250
(1285--4800)
0.000 2550
(2010--3945)
0.000
   GC 955
(335--2626)
  810
(600--1360)
  1530bc
(860--2400)
 
  L CC 384
(0--1284)
  340
(275--710)
  640c
(300--1630)
 
Gly54
Asp
A GG 2249
(1333--3352)
0.000 1370
(825--3925)
0.000 2280
(1500--2800)
0.000
   GA 315
(3--540)
  460b
(335--695)
  475b
(298--695)
 
  B AA 0   270
(135-280)
  270  
+4 P CC 1039
(215--2668)
0.036 800
(430--1363)
0.367 1910bc
(1045--2635)
0.470
   CT 2182
(1187--2826)
  800
(370--4265)
  1605
(488--3013)
 
  Q TT 4823   2895
(830--4960)
  3570  
  1. Data are expressed as the median and interquartile range (IQR; 25% to 75%). a = P-value based on the Kruskal--Wallis or Mann--Whitney U test. Statistical differences in the mannose-binding lectin (MBL) levels were analyzed according to genotype within each subgroup. b = P < 0.05 vs. the control group. c = P < 0.05 vs. the severe sepsis group. SNP = single nucleotide polymorphism.