Table 2 Genotype frequencies for Gly54Asp in mannose-binding lectin between patients and controls and between septic patients
From: Association of mannose-binding lectin-2 genotype and serum levels with prognosis of sepsis
Locus | Allele | Group N (%) | Group n (%) | OR (95% CI) | P | Adjusted ORa (95% CI) | P | ||
|---|---|---|---|---|---|---|---|---|---|
Sepsis | Control | ||||||||
GG | A | 185 | 72.27 | 262 | 66.16 | ||||
GA | 64 | 25.00 | 115 | 29.04 | 0.788 (0.550, 1.129) | 0.194 | 0.815 (0.507, 1.312) | 0.400 | |
AA | B | 7 | 2.73 | 19 | 4.80 | 0.522 (0.215, 1.266) | 0.150 | 0.388 (0.127, 1.180) | 0.095 |
GG | 185 | 72.27 | 262 | 66.16 | |||||
GA/AA | 71 | 27.73 | 134 | 33.84 | 0.750 (0.532, 1.058) | 0.102 | 0.742 (0.471, 1.167) | 0.196 | |
Septic shock | Severe sepsis | ||||||||
GG | A | 144 | 77.84 | 41 | 57.75 | ||||
GA | 37 | 20.00 | 27 | 38.03 | 0.362 (0.199, 0.658) | 0.001 | 0.368 (0.202, 0.672) | 0.001 | |
AA | B | 4 | 2.16 | 3 | 4.23 | 0.389 (0.084, 1.807) | 0.228 | 0.381 (0.081, 1.794) | 0.222 |
GG | 144 | 77.84% | 41 | 57.75% | |||||
GA/AA | 41 | 22.16% | 30 | 42.25% | 0.365 (0.205, 0.650) | 0.001 | 0.370 (0.207, 0.661) | 0.001 | |