Table 1 Baseline characteristics of the patients at day one of severe sepsis or septic shock
From: Association of mannose-binding lectin-2 genotype and serum levels with prognosis of sepsis
Characteristic | Severe sepsis (n = 77) | Septic shock (n = 189) | P value |
|---|---|---|---|
Age | 65 (57-71) | 65 (53-71) | NS |
Male gender, % | 58.4 | 65.6 | NS |
APACHE II score | 19 (15-24) | 26 (21-34) | 0.000 |
SOFA score | 9 (7-11) | 13 (10-15) | 0.000 |
Admission route, n (%) | NS | ||
Medical | 73 (94.8) | 167 (88.4) | |
Surgical | |||
elective/emergent | 3 (3.9)/1 (1.3) | 18 (9.5)/4 (2.1) | |
Prior or preexisting disease, n (%) | NS | ||
Chronic liver disease | 6 (7.8) | 17 (9.0) | |
Chronic pulmonary disease | 1 (1.3) | 7 (3.7) | |
Congestive heart disease | 2 (2.6) | 4 (2.1) | |
Diabetes mellitus | 5 (2.6) | ||
Malignancy | 14 (18.2) | 44 (23.3) | |
Neurologic disease | 5 (6.5) | 10 (5.3) | |
Othersa | 3 (3.9) | 7 (3.7) | |
≥ 2 diseases | 7 (9.1) | 22 (11.6) | |
None | 39 (50.7) | 73 (38.6) | |
Type of infection, n (%) | 0.034 | ||
Pneumonia | 20 (26.0) | 80 (42.3) | |
Intraabdominal infection | 15 (19.5) | 34 (18.0) | |
Biliary | 20 (26.0) | 19 (10.1) | |
Urinary tract infection | 11 (14.3) | 21 (11.1) | |
Bacteremia | 2 (2.6) | 4 (2.1) | |
Wound infection | 5(6.5) | 12 (6.3) | |
Othersb | 4 (5.2) | 19 (10) | |
Positive culture, n (%) | 45.5 | 37.0 | NS |
Gram-negative | 68.6 | 60.0 | |
Gram-positive | 17.1 | 31.4 | |
Mixed | 11.4 | 2.9 | |
Anaerobe | 2.9 | 2.9 | |
Fungi | 2.9 | ||
Mechanical ventilation, % | 51.9 | 79.3 | <0.0001 |
Renal replacement, % | 9.1 | 31.2 | <0.0001 |
Length of ICU stay, days | 4 (3-9) | 10 (6-19) | <0.0001 |
Nosocomial infection, % | 23.4 | 22.2 | NS |