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Table 1 Baseline characteristics of the patients at day one of severe sepsis or septic shock

From: Association of mannose-binding lectin-2 genotype and serum levels with prognosis of sepsis

Characteristic Severe sepsis
(n = 77)
Septic shock
(n = 189)
P value
Age 65 (57-71) 65 (53-71) NS
Male gender, % 58.4 65.6 NS
APACHE II score 19 (15-24) 26 (21-34) 0.000
SOFA score 9 (7-11) 13 (10-15) 0.000
Admission route, n (%)    NS
Medical 73 (94.8) 167 (88.4)  
Surgical    
elective/emergent 3 (3.9)/1 (1.3) 18 (9.5)/4 (2.1)  
Prior or preexisting disease, n (%)    NS
Chronic liver disease 6 (7.8) 17 (9.0)  
Chronic pulmonary disease 1 (1.3) 7 (3.7)  
Congestive heart disease 2 (2.6) 4 (2.1)  
Diabetes mellitus   5 (2.6)  
Malignancy 14 (18.2) 44 (23.3)  
Neurologic disease 5 (6.5) 10 (5.3)  
Othersa 3 (3.9) 7 (3.7)  
≥ 2 diseases 7 (9.1) 22 (11.6)  
None 39 (50.7) 73 (38.6)  
Type of infection, n (%)    0.034
Pneumonia 20 (26.0) 80 (42.3)  
Intraabdominal infection 15 (19.5) 34 (18.0)  
Biliary 20 (26.0) 19 (10.1)  
Urinary tract infection 11 (14.3) 21 (11.1)  
Bacteremia 2 (2.6) 4 (2.1)  
Wound infection 5(6.5) 12 (6.3)  
Othersb 4 (5.2) 19 (10)  
Positive culture, n (%) 45.5 37.0 NS
Gram-negative 68.6 60.0  
Gram-positive 17.1 31.4  
Mixed 11.4 2.9  
Anaerobe 2.9 2.9  
Fungi   2.9  
Mechanical ventilation, % 51.9 79.3 <0.0001
Renal replacement, % 9.1 31.2 <0.0001
Length of ICU stay, days 4 (3-9) 10 (6-19) <0.0001
Nosocomial infection, % 23.4 22.2 NS
  1. Data are presented as the median and interquartile range (25% to 75%). a = rheumatologic disease, inflammatory bowel disease; b = cellulitis, meningitis, leptospirosis.
  2. APACHE II = Acute Physiology, Age, and Chronic Health Evaluation II; ICU = intensive care unit; NS = not significant; SOFA = Sequential Organ Failure Assessment.