Late initiation of renal replacement therapy is associated with worse outcomes in acute kidney injury after major abdominal surgery

Table 1 RIFLE classification [24] for acute kidney injury

	GFR criteria	Urine output criteria
Risk	Increase plasma creatinine ×1.5 or GFR decrease > 25%	< 0.5 ml/kg/h × 6 h
Injury	Increase plasma creatinine ×2 or GFR decrease > 50%	< 0.5 ml/kg/h × 12 h
Failure	Increase plasma creatinine ×3 or GFR decrease > 75%, or serum creatinine ≥ 4 mg/dL with an acute rise > 0.5 mg/dL	< 0.3 ml/kg/h × 24 h or anuria ×12 h
Loss	Persistent ARF = complete loss of kidney function > 4 wk
ESRD	End-stage renal disease (> 3 month)

ARF, acute renal failure; ESRD = end stage renal disease; GFR = glomerular filtration rate; h = hours.

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