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Table 1 Comparison of demographic variables and clinical outcomes between PRIS and non-PRIS patients

From: Incidence of propofol-related infusion syndrome in critically ill adults: a prospective, multicenter study

  PRIS
n = 11
No PRIS
n = 1006
P value
Age (years)A 58 ± 14 56 ± 18 0.64
Male (%) 82 65 0.4
APACHE II scoreA 25 ± 6 20 ± 6 0.03
Admitting service (%)    
   Medicine 36 35 0.82
   Surgery    
   Neurosurgery 9 25 0.39
   Trauma 9 23 0.47
   Other surgery 46 17 0.04
Primary reason for ICU admit (%)    
   Trauma 18 23 1.0
   Surgery 28 21 0.89
   Neurological 9 20 0.6
   Respiratory failure 36 17 0.2
   Cardiac 0 9 0.61
   Other 9 10 0.77
Past medical history (%)    
   Coronary artery disease 27 30 0.89
   Malignancy 36 18 0.24
   Congestive heart failure 18 18 0.71
   Diabetes 18 16 0.83
   Chronic obstructive pulmonary disease 27 10 0.12
   Other 9 12 0.87
Use of propofol dose >83 μg/kg/min (%) 18 10 0.68
Duration of propofol (days)B 5 (3-7) 4 (3-7) 0.43
Number of PRIS clinical manifestationsC 5 (2-7) 1 (0-6) 0.0001
Duration of ICU stay (days)B 14 (10-18) 12 (7-20) 0.4
ICU mortality (%) 18 20 0.82
Hospital mortality (%) 18 21 0.88
  1. APACHE = acute physiology and chronic health evaluation; ICU = intensive care unit; PRIS = propofol-relation infusion syndrome.
  2. AMean ± standard deviation
  3. BMedian (interquartile range)
  4. CMedian (Range)