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Table 2 Risk factors for extubation complications

From: Clinical review: Post-extubation laryngeal edema and extubation failure in critically ill adult patients

Outcome measure

Study

Year

Risk factors

Laryngeal injury

Colice and colleagues [2]

1989

Persistent laryngeal neuromotor activity, tracheostomy

 

Kastanos and colleagues [17]

1983

Severe respiratory failure, high cuff pressure, duration of endotracheal intubation, secretion infection

 

Esteller and colleagues [19]

2005

Longer duration of intubation, tracheostomy, number of days in the intensive care unit

Laryngeal edema

Darmon and colleagues [4]

1992

Duration of intubation (>36 hours), gender (female)

 

Francois and colleagues [6]

2007

Trauma at admission, gender (female), short duration of intubation (<7 days), smaller height to tube diameter ratio, absence of methylprednisolone pre treatment

Post-extubation stridor

Cheng and colleagues [3]

2006

Gender (female), lower Glasgow coma score, nonsedation treatment

 

Sandhu and colleagues [26]

2000

Duration of intubation (>3 days)

 

Daley and colleagues [9]

1996

Tracheostomy, time to reintubation

 

Ho and colleagues [7]

1996

Gender (female)

 

Jaber and colleagues [30]

2003

High SAPS II, medical patients, difficult intubation, history of self-extubation, prolonged intubation, high cuff pressure

 

Kriner and colleagues [8]

2005

Gender (female), duration of intubation (>6 days), ratio tube size to laryngeal size >45%

 

Wang and colleagues [14]

2007

Gender (female)

 

Maury and colleagues [25]

2004

Gender (female)

 

Erginel and colleagues [15]

2005

Duration of ventilation (>5 days), body mass index (>26.5)

Reintubation

Daley and colleagues [9]

1996

Tracheostomy, post-extubation stridor

 

Jaber and colleagues [30]

2003

Post-extubation stridor

 

Epstein and colleagues [1]

1997

APACHE II score, age, cardiopulmonary cause for reintubation

 

Sandhu and colleagues [26]

2000

Duration of previous intubation (>3 days)

  1. APACHE, Acute Physiology and Chronic Health Evaluation; SAPS, Simplified Acute Physiology Score.