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Table 1 Incidence of post-extubation stridor and laryngeal edema

From: Clinical review: Post-extubation laryngeal edema and extubation failure in critically ill adult patients

Study Year Extubations or participants (n) Cases (n) % Definition
Post-extubation stridor      
   Epstein and colleagues [1] 1998 74 11 15 Stridor with resolution upon reintubation
   Maury and colleagues [25] 2004 115 4 3.5 High-pitched inspiratory wheeze within 24 hours of extubation with respiratory rate >30/minute
   Sandhu and colleagues [26] 2000 110 13 11.8 High-pitched inspiratory wheeze requiring medical intervention
   Miller and Cole [27] 1996 100 6 6 High-pitched inspiratory wheeze requiring medical intervention
   Kriner and colleagues [8] 2005 462 20 4.3 Inspiratory grunting, whistling or wheezing requiring medical intervention within 24 hours after extubation
   Ding and colleagues [28] 2006 51 4 7.8 High-pitched inspiratory wheeze associated with respiratory distress
   Colice and colleagues [2] 1989 82 5 6 Post-extubation stridor or hoarseness
   Ho and colleagues [7] 1996 38a 10 26 Crowing sound on inspiration
   Jaber and colleagues [30] 2003 112 13 12 High-pitched inspiratory wheeze requiring medical intervention
   Cheng and colleagues [3] 2006 43 13 30.2 High-pitched inspiratory wheeze requiring medical intervention (in control group of intervention arm with positive cuff leak test)
   de Bast and colleagues [36] 2002 76 10 13 Inspiratory wheezing
   Lee and colleagues [13] 2007 40 11 27.5 Stridor heard with stethoscope
Laryngeal edema      
   Francois and colleagues [6] 2007 343a 76 22 Stridor with respiratory distress with need for medical intervention (minor) or severe respiratory distress needing reintubation <24 hours after extubation (major)
   Darmon and colleagues [4] 1992 663 28 4.2 Laryngeal dyspnea and/or stridor (minor laryngeal edema) or the need for reintubation due to laryngeal edema as confirmed by endoscopy (major laryngeal edema)
   de Bast and colleagues [36] 2002 76 8 11 Stridor with respiratory distress requiring reintubation within 24 hours, confirmed by fiberoptic examination or direct view
   Chung and colleagues [55] 2006 95 35 36.8 Near total occlusion of the airway as seen on video bronchoscopy
  1. aPlacebo group.