Table 1 Comparison of MMP-9, MMP-10, and TIMP-1 serum levels between sepsis patients and controls (median and 25 ^th to 75 ^th percentiles are shown)

Gender female: number (%)

13 (26.0)

64 (33.3)

0.11

Age (years)

57 (50-63)

60 (49-70)

0.39

MMP-9 (ng/ml)

498 (350-735)

676 (308-1,164)

0.07

TIMP-1 (ng/ml)

226 (213-241)

618 (445-831)

<0.001

MMP-10 (pg/ml)

466 (288-614)

1,880 (1,217-3,285)

<0.001

MMP-9/TIMP-1 (ratio)

2.19 (1.57-3.01)

1.16 (0.49-2.24)

<0.001

MMP-10/TIMP-1 (ratio)

2.07 (1.17-2.84)

3.09 (2.08-5.06)

<0.001