A new integrative weaning index of discontinuation from mechanical ventilation

Table 2 Accuracy, likelihood ratio, probability for weaning success when test is positive and probability for weaning success when test is negative of the indexes used to predict the weaning outcome in the prospective-validation data set

Index	Sensitivity (%)	Specificity (%)	Positive predictive value (%)	Negative predictive value (%)	Diagnostic accuracy (%)	LR+	LR-	P(W+/T+)	P(W+/T-)
PaO₂/FiO₂	0.60	0.67	0.91	0.23	0.61	1.79	0.61	0.91	0.77
Cst,rs	0.82	0.76	0.95	0.44	0.81	3.40	0.23	0.95	0.56
IWI	0.97	0.94	0.99	0.86	0.97	16.05	0.03	0.99	0.14
P 0.1	0.76	0.70	0.93	0.35	0.75	2.52	0.34	0.93	0.65
f	0.79	0.58	0.91	0.33	0.76	1.87	0.36	0.91	0.67
Vt	0.76	0.73	0.94	0.36	0.76	2.81	0.32	0.94	0.64
f/Vt × P 0.1	0.76	0.73	0.94	0.36	0.76	2.81	0.32	0.94	0.64
f/Vt	0.81	0.73	0.94	0.41	0.80	2.99	0.26	0.94	0.59

Cst,rs = static compliance of the respiratory system; f = respiratory rate; f/Vt ratio = frequency to tidal volume ratio; IWI = integrative weaning index; LR+ = likelihood ratio of positive test; LR- = likelihood ratio of negative test; P 0.1 = airway occlusion pressure; PaO₂/FiO₂ ratio = ratio of arterial oxygen tension to fraction of inspired oxygen; P(W+/T+) = probability for weaning success if test is positive; P(W+/T-) = probability for weaning success if test is negative; Vt = tidal volume.

ISSN: 1364-8535