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Table 4 Characteristics of 32 patients according to ventilator support required

From: Intensive care adult patients with severe respiratory failure caused by Influenza A (H1N1)v in Spain

Variable Non-ventilated (n = 8) Non-invasive ventilation Initially intubated (n = 16)
   Successful (n = 2) Failure (n = 6)  
APACHE II score     
Mean (SD) 9.5 (4.9) 4 to 16 9.5 (0.7) 9 to 10 15.3 (5.6) 10 to 24 15.2 (7.6) 8 to 38
IQR 25th to 75th     
SOFA score     
Mean (SD) 4.7 (1.7) 2.5 (0.7)* 8.1 (2.3)** 7.8 (3.5)
IQR 25th to 75th 3 to 7 2 to 3 5 to 11 4 to 16
Age, years     
Mean (SD) 39.2 (14.7) 42.5 (13.4) 44.0 (15.1) 38.7 (14.0)
IQR 25th to 75th 17 to 58 33 to 52 10 to 57 16 to 70
Opacity lung quadrants     
Mean (SD) 2.9 (1.2) 2.5 (2.1) 2.8 (0.9) 3.3 (1.1)
LDH, U/L     
Mean (SD) 751 (361) 1140 (374) 918 (408) 2170 (3400)
IQR 25th to 75th 195 to 1166 880 to 1400 354 to 1450 440 to 12200
CK, U/L     
Mean (SD) 2480 (4500) 2800 (3200) 4850 (4200) 2300 (3800)
IQR 25th to 75th 66 to 9300 500 to 5100 122 to 9400 207 to 10800
28-day mortality, n (%)*** 0 0 2 (33) 4 (25)
  1. * vs. ** P = 0.01
  2. *** Two additional patients died by refractory hypoxemia after 31 and 65 days of mechanical ventilation.
  3. APACHE II = Acute Physiology And Chronic Health Evaluation II; CK = creatine kinase; IQR = interquartile range; LDH = lactate dehydrogenase; SD = standard deviation; SOFA = Sequential Organ Failure Assessment.