Effects on management and outcome of severe sepsis and septic shock patients admitted to the intensive care unit after implementation of a sepsis program: a pilot study

Table 2 Percentage of patients with completion of interventions and bundles subdivided for semesters of analysis

Intervention	Total	January to June 2005	July to December 2005	January to June 2006	July to December 2006	January to June 2007
Blood cultures collection*	83	77	73	80	92	95
Antibiotic therapy (3 hours)*	95	92	82	100	100	100
Infection source control* ^§	86	85	82	70	92	100
Adequate fluid resuscitation	98	92	100	100	100	95
ScvO₂ optimization*	61	46	45	50	92	70
Glycaemia control	93	92	100	100	92	80
Low-dose hydrocortisone*	73	31	82	80	85	90
rhAPC*	66	54	45	70	77	85
PiP < 30 cmH₂O*	79	46	82	80	85	100
6-hours bundle	45	38	9	20	77	60
24-hours bundle	45	8	36	50	62	60
All interventions	22	8	0	10	46	35
Sepsis team admissions*	33	0	0	0	85	55

Data are expressed as percentage of patients. * P < 0.05 comparing the semesters; ^§ Source control details: 38 surgical patients: 21 control by surgery, 3 radiological drainage, 8 control not necessary, 6 control not achieved within 6 hours. 29 medical patients: 6 radiological drainage, 6 central venous line removal, 13 control not necessary, 4 control not achieved within 6 hours.
PiP = plateau inspiratory pressure; rhAPC = recombinant human activated C protein; ScvO₂ = central venous oxygen saturation.

ISSN: 1364-8535