Effects of inducible nitric oxide synthase inhibition or norepinephrine on the neurovascular coupling in an endotoxic rat shock model

Table 3 Data from cytokine and destruction marker measurements as group averaged data ± standard deviation

	NSE ng/l	S-100B ng/ml	IL 6 pg/ml	TNF-α pg/ml	IFN-γ pg/ml
Control	0.29 ± 0.14	0.63 ± 0.3	93 ± 28	60 ± 22	32 ± 3
5 mg/kg LPS	1.8 ± 0.9	13 ± 8.6	5498 ± 1980	1868 ± 977	1600 ± 540
5 mg/kg LPS+1400W	1.6 ± 0.9	11 ± 9.7	4998 ± 1780	1655 ± 877	1800 ± 820
5 mg/kg LPS +NE	2.2 ± 0.4	10 ± 7.6	5300 ± 1654	1285 ± 592	1960 ± 660

Compared with control destruction markers and cytokine levels significantly increased in the sepsis groups but did not differ between sepsis groups.
1400W = N-(3-(aminomethyl)benzyl)acetamidine; IFN = interferon; IL = interleukin; LPS = lipopolysaccharide; NE = norepinephrine; NSE = neuron specific enolase.

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